Adult human neural crest–derived cells for articular cartilage repair

• DOI: 10.1126/scitranslmed.3009688
• Publication Date: 2014-08-27T18:48:40Z
• Authors: Karoliina Pelttari; Benjamin Pippenger; Marcus Mumme; Sandra Feliciano; Celeste Scotti; Pierre Mainil-Varlet; Alfredo Procino; Brigitte von Rech...; Thomas Schwamborn; Marcel Jakob; Clemente Cillo; Andrea Barbero; Ivan Martin
• Keywords: Adult; Cartilage, Articular; Homeodomain Proteins; 0301 basic medicine; Wound Healing; Neuronal Plasticity; Knee Joint; Gene Expression Profiling; Goats; Pilot Projects; Middle Aged; Transplantation, Autologous; Coculture Techniques; Mice; 03 medical and health sciences; Gene Expression Regulation; Neural Crest; Animals; Humans; Cell Proliferation

HOX -negative, differentiated neural crest–derived adult cells from the nasal septum display self-renewal capacity and environmental plasticity and are compatible for articular cartilage repair.