Metabolic differentiation of early Lyme disease from southern tick–associated rash illness (STARI)

• DOI: 10.1126/scitranslmed.aal2717
• Publication Date: 2017-08-16T18:25:51Z
• Authors: Claudia R. Molins; Laura V. Ashton; Gary P. Wormser; Barbara G. Andre; Ann M. Hess; Mark J. Delorey; Mark A. Pilgard; Barbara J. Johnson; Kristofor Webb; M. Nurul Islam; Adoracion Pegalaj...; Irida Molla; Mollie W. Jewett; John T. Belisle
• Keywords: Male; 0301 basic medicine; Lyme Disease; Geography; Exanthema; Middle Aged; Tick Infestations; 3. Good health; Diagnosis, Differential; 03 medical and health sciences; Case-Control Studies; Metabolome; Animals; Humans; Metabolomics; Computer Simulation; Female; Metabolic Networks and Pathways

Metabolic profiling provides a biochemical signature to objectively differentiate two illnesses with nearly identical clinical presentations, early Lyme disease and STARI.