Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis

• DOI: 10.1126/scitranslmed.aap8307
• Publication Date: 2018-05-16T18:05:17Z
• Authors: Kevin J. Frankowski; Chen Wang; Samarjit Patnaik; Frank J. Schoenen; Noel Southall; Dandan Li; Yaroslav Teper; Wei Sun; Irawati Kandela; Deqing Hu; Christopher Dextras; Zachary Knotts; Yansong Bian; John Norton; Steve Titus; Marzena A. Lewand...; Yiping Wen; Katherine I. Farley; Lesley Mathews Gr...; Jamey Sultan; Zhaojing Meng; Ming Zhou; Tomas Vilimas; Astin S. Powers; Serguei Kozlov; Kunio Nagashima; Humair S. Quadri; Min Fang; Charles Long; Ojus Khanolkar; Warren Chen; Jinsol Kang; Helen Huang; Eric Chow; Esthermanya Goldberg; Coral Feldman; Romi Xi; Hye Rim Kim; Gary Sahagian; Susan J. Baserga; Andrew Mazar; Marc Ferrer; Wei Zheng; Ali Shilatifard; Jeffrey Aubé; Udo Rudloff; Juan Jose Marugan; Sui Huang
• Keywords: Compartment (ship)

A compound that reduces the prevalence of perinucleolar compartment in cancer cells inhibits metastasis vivo.