A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix

• DOI: 10.1126/scitranslmed.aar4953
• Publication Date: 2019-04-24T23:10:13Z
• Authors: Howard J. Seeherman; Stephen P. Berasi; Christopher T. Brown; Robert X. Martinez; Z. Sean Juo; Scott Jelinsky; Michael J. Cain; Jaclyn Grode; Kathleen E. Tumelty; Marc Bohner; Orly Grinberg; Nadav Orr; Oded Shoseyov; Jeroen Eyckmans; Christopher Chen; Pablo R. Morales; Christopher G. Wi...; Eric J. Vanderploeg; John M. Wozney
• Keywords: Chimera (genetics)

BV-265, a BMP-2/BMP-6/activin A chimera, delivered in composite matrix generates bone repair nonhuman primates at lower concentrations than BMP-2.