Characterization of a Genetic Element Carrying the Macrolide Efflux Gene mef (A) in Streptococcus pneumoniae
DNA, Bacterial
0301 basic medicine
Molecular Sequence Data
Membrane Proteins
Biological Transport
Drug Resistance, Microbial
Sequence Analysis, DNA
Chromosomes, Bacterial
Virginiamycin
Anti-Bacterial Agents
3. Good health
resistance
Open Reading Frames
03 medical and health sciences
Streptococcus pneumoniae
Bacterial Proteins
DNA Transposable Elements
Humans
Macrolides
DOI:
10.1128/aac.44.9.2585-2587.2000
Publication Date:
2002-07-27T10:06:42Z
AUTHORS (5)
ABSTRACT
ABSTRACT
The
mef
(A) gene from a clinical isolate of
Streptococcus pneumoniae
exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn
1207.1
, which contained 8 open reading frames.
orf2
encodes a resolvase/invertase, and
orf5
is a homolog of the macrolide-streptogramin B resistance gene
msr
(SA).
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