In Vitro Metronidazole and Tinidazole Activities against Metronidazole- Resistant Strains of Trichomonas vaginalis

• DOI: 10.1128/aac.47.4.1407-1409.2003
• Publication Date: 2003-03-24T19:46:16Z
• Authors: Andrea L. Crowell; Kolby A. Sanders-...; W. Evan Secor
• Keywords: Tinidazole; Trichomonas; Trichomonas Vaginitis

The in vitro activities of tinidazole and metronidazole against Trichomonas vaginalis isolates clinically resistant to were compared. Minimal lethal concentrations (MLCs) significantly lower than MLCs metronidazole. Increased resistance correlated with increased resistance. These data support a role for the treatment trichomoniasis.