Pleiotropic Effects of GacA on Pseudomonas fluorescens Pf0-1 In Vitro and in Soil

• DOI: 10.1128/aem.00819-13
• Publication Date: 2013-06-29T07:38:20Z
• Authors: Sarah C. Seaton; Mark W. Silby; Stuart B. Levy
• Keywords: 0301 basic medicine; 03 medical and health sciences; Bacterial Proteins; Biofilms; Genetic Complementation Test; Pseudomonas fluorescens; Gene Deletion; Soil Microbiology

ABSTRACT

Pseudomonas species can exhibit phenotypic variation resulting from gacS or gacA mutation. P. fluorescens Pf0-1 is a gacA mutant and exhibits pleiotropic changes following the introduction of a functional allele. GacA enhances biofilm development while reducing dissemination in soil, suggesting that alternative Gac phenotypes enable Pseudomonas sp. to exploit varied environments.