Commonalities and Differences in Regulation of N -Acyl Homoserine Lactone Quorum Sensing in the Beneficial Plant-Associated Burkholderia Species Cluster

• DOI: 10.1128/aem.03086-09
• Publication Date: 2010-05-01T01:29:02Z
• Authors: Zulma Rocío Suá...; Giulia Devescovi; Mike Myers; Letícia Hallack; Lucia Mendonça-P...; Jesús Caballero-...; Vittorio Venturi
• Keywords: Burkholderia cepacia complex; Homoserine

The genus Burkholderia includes over 60 species isolated from a wide range of environmental niches and can be tentatively divided into two major clusters. first cluster pathogens such as glumae, B. pseudomallei, mallei 17 well-studied the cepacia complex. other recently established comprises at least 29 nonpathogenic species, which in most cases have been found to associated with plants. It was previously that kururiensis, member latter cluster, possesses an N-acyl homoserine lactone (AHL) quorum-sensing (QS) system designated "BraI/R," is all plant-associated cluster. In present study, BraI/R-like systems were characterized xenovorans unamae BraI/R(XEN) BraI/R(UNA) systems, respectively. Several phenotypes analyzed, it determined exopolysaccharide positively regulated by BraIR-like unamae, xenovorans, highlighting commonality targets. However, three also revealed differences targets since biofilm formation plant colonization differentially regulated. addition, second AHL QS XenI2/R2 unpaired LuxR solo protein BxeR identified LB400(T). are not transcriptionally regulating each other, whereas negatively xenI2. proteins widespread conclusion, study represents extensive analysis demonstrating both commonalities differences, probably reflecting adaptations various species.