Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1

• DOI: 10.1128/jb.173.21.7024-7028.1991
• Publication Date: 2016-11-14T17:11:03Z
• Authors: A Stevens; C L Hsu; K R Isham; F W Larimer
• Keywords: Exoribonuclease; Spacer DNA; Cleavage (geology)

The portion of the internal transcribed spacer 1 found on 20S pre-rRNA accumulates in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1, showing that an endonucleolytic cleavage at 3' terminus 18S rRNA is involved to mature conversion. Smaller fragments sequence are also found. may be as a cytoplasmic RNase hydrolysis spacer.