Differential increase in topoisomerase II in simian virus 40-infected cells

• DOI: 10.1128/jvi.64.2.918-921.1990
• Publication Date: 2020-01-06T15:49:05Z
• Authors: R Rainwater; K Mann
• Keywords: Simian

The time course of expression topoisomerase I, II, and simian virus 40 (SV40) large tumor (T) antigen was determined in whole-cell extracts uninfected versus SV40-infected TC7 cells. After a minor increase, the level I remained fairly constant throughout both In contrast, II increased markedly cells but not following appearance SV40 T antigen.