A Spontaneous rapZ Mutant Impairs Infectivity of Lytic Bacteriophage vB_EcoM_JS09 against Enterotoxigenic Escherichia coli

• DOI: 10.1128/msphere.01286-20
• Publication Date: 2021-03-05T14:30:47Z
• Authors: Yan Zhou; Hongduo Bao; Hui Zhang; Maoda Pang; Shujiao Zhu; Ran Wang
• Keywords: Lytic cycle; Infectivity; Phagemid

The development of phage-resistant bacteria is a challenging problem for phage therapy. However, our knowledge resistance mechanisms still limited.