Absolute Proteome Quantification in the Gas-Fermenting Acetogen Clostridium autoethanogenum

• DOI: 10.1128/msystems.00026-22
• Publication Date: 2022-04-06T13:00:26Z
• Authors: Kaspar Valgepea; Gert Talbo; Nobuaki Takemori; Ayako Takemori; Christina Ludwig; Vishnuvardhan Mah...; Alexander P. Mueller; Ryan Tappel; Michael Köpke; Séan Dennis Simpson; Lars Keld Nielsen; Esteban Marcellin
• Keywords: Proteomics; Carbon Monoxide; 0303 health sciences; Proteome; Ethanol; genome-scale metabolic modeling; acetogen; Carbon Dioxide; Acetogen; metabolomics; Microbiology; QR1-502; Carbon; Metabolic modeling; 03 medical and health sciences; proteomics; metabolic modeling; gGenome-scale metabolic modeling; 13. Climate action; Metabolomics; Gas fermentation; Gases; gas fermentation; Research Article

Acetogen bacteria are important for maintaining biosustainability as they can recycle gaseous C 1 waste feedstocks (e.g., industrial waste gases and syngas from gasified biomass or municipal solid waste) into fuels and chemicals. Notably, the acetogen Clostridium autoethanogenum is being used as a cell factory in industrial-scale gas fermentation.