Revealing the Characteristics of Glucose- and Lactate-Based Chain Elongation for Caproate Production by Caproicibacterium lactatifermentans through Transcriptomic, Bioenergetic, and Regulatory Analyses

• DOI: 10.1128/msystems.00534-22
• Publication Date: 2022-09-08T12:00:50Z
• Authors: Huilin Wang; Weicheng Zhou; Jiangjing Gao; Cong Ren; Yan Xu
• Keywords: 0301 basic medicine; Caproicibacterium lactatifermentans; caproate-producing bacterium; lactate utilization; Microbiology; QR1-502; 6. Clean water; transcriptomics; 03 medical and health sciences; Glucose; Adenosine Triphosphate; Lactic Acid; Transcriptome; Caproates; Oxidation-Reduction; transcriptional regulator; Research Article

Caproicibacterium lactatifermentans is a unique and robust caproate-producing bacterium in the family Oscillospiraceae due to its lactate utilization capability, whereas close relatives such as amylolyticum , Caproiciproducens galactitolivorans Caproicibacter fermentans cannot utilize but produce main fermentation end product. Moreover, C. can also several saccharides glucose maltose.