Semirapid Detection of Piperacillin/Tazobactam Resistance and Extended-Spectrum Resistance to β-Lactams/β-Lactamase Inhibitors in Clinical Isolates of Escherichia coli

• DOI: 10.1128/spectrum.00801-21
• Publication Date: 2021-10-25T16:21:39Z
• Authors: Ángel Rodríguez-V...; Alicia Gutiérrez ...; Lydia Gálvez-Benitez; Jerónimo Pachón; José Antonio Lepe; Younes Smani
• Keywords: Sulbactam; Tazobactam; Piperacillin/tazobactam; Amp resistance

Piperacillin/tazobactam (TZP) is a β-lactam/β-lactamase inhibitor (BL/BLI) recommended for the empirical treatment of severe infections. The excessive and indiscriminate use TZP has promoted emergence TZP-resistant Escherichia coli isolates. Recently, we demonstrated that may contribute to development