Safety Evaluation and Probiotic Potency Screening of Akkermansia muciniphila Strains Isolated from Human Feces and Breast Milk

• DOI: 10.1128/spectrum.03361-22
• Publication Date: 2023-02-14T14:28:24Z
• Authors: Fengyi Hou; Jingyi Tang; Yangyang Liu; Yafang Tan; Ye Wang; Lijun Zheng; Debao Liang; Yuqing Lin; Likun Wang; Zhiyuan Pan; Ruifu Yang; Yujing Bi; Fachao Zhi
• Keywords: 0301 basic medicine; 03 medical and health sciences; 3. Good health; Research Article

In this study, we isolated 30 strains of Akkermansia muciniphila from different samples of human feces, and for the first time we isolated an A. muciniphila strain from human breast milk. This isolation verified the existence of microbes in human breast milk, which suggests that A. muciniphila can be vertically propagated from mother to infant and participates in the formation of the early gut microbiome.