Intrapericardial streptokinase in purulent pericarditis

• DOI: 10.1136/adc.80.3.275
• Publication Date: 2009-01-07T21:17:23Z
• Authors: R. Juneja; S. S Kothari; A. Saxena; R. Sharma; A. Joshi
• Keywords: Staphylococcus aureus; Infant; Staphylococcal Infections; 3. Good health; 03 medical and health sciences; Instillation, Drug; 0302 clinical medicine; Echocardiography; Evaluation Studies as Topic; Child, Preschool; Humans; Pericarditis; Streptokinase; Thrombolytic Therapy; Child; Pericardium

Six consecutive children with proven purulent pericarditis were treated pericardial irrigation streptokinase. Mean (SD) 861 (678) ml (range 240-2000) of thick fluid was drained, and five had complete clearance the pus within 3-8 days. One child developed intrapericardial haemorrhage a submitral pseudoaneurysm underwent patch closure neck aneurysm as well anterior pericardiectomy. Follow up 13 to 30 months revealed no constriction.