Cost effectiveness of strategies to combat cardiovascular disease, diabetes, and tobacco use in sub-Saharan Africa and South East Asia: mathematical modelling study

• DOI: 10.1136/bmj.e607
• Publication Date: 2012-03-04T21:51:36Z
• Authors: M. Ortegon; S. Lim; D. Chisholm; S. Mendis
• Keywords: Adult; Male; Asia; Economics; Cost-Benefit Analysis; Southeastern; Smoking Prevention; Tobacco use disorder; Article; Diabetes mellitus; Theoretical; Models; Cost benefit analysis; 80 and over; Diabetes Mellitus; Humans; Southeast asia; Theoretical model; Middle aged; southeastern; theoretical; Africa South of the Sahara; Asia, Southeastern; Aged; Aged, 80 and over; Research; Smoking; Cost-benefit analysis; 1. No poverty; Tobacco Use Disorder; Middle Aged; Models, Theoretical; Cardiovascular disease; 3. Good health; Cardiovascular diseases; Cardiovascular Diseases; Africa south of the sahara; Female; Tobacco dependence; Human

To determine the relative costs and health effects of interventions to combat cardiovascular disease, diabetes, tobacco related disease in order guide allocation resources developing countries.Cost effectiveness analysis 123 single or combined prevention treatment strategies for smoking by means a lifetime population model.Two World Health Organization sub-regions world: countries sub-Saharan Africa with very high adult child mortality (AfrE) South East Asia (SearD).Demographic epidemiological data were taken from WHO databases global burden disease. Estimates intervention coverage, effectiveness, resource needs drawn clinical trials, observational studies, guidelines. Unit WHO-CHOICE (Choosing Interventions that are Cost-Effective) price database.Cost per disability adjusted life year (DALY) averted, expressed international dollars ($Int) 2005.Most studied considered highly cost effective, meaning they generate one healthy at <$Int2000 (which is gross domestic product capita two regions here). offer particularly good monetary value, which could be prioritised implementation scale up, include demand reduction Framework Convention Tobacco Control (<$Int950 <$Int200 DALY averted AfrE SearD respectively); combination drug therapy people >25% chance experiencing event over next decade, either alone together specific multidrug regimens secondary post-acute ischaemic heart stroke (<$Int150 <$Int230 retinopathy screening glycaemic control patients diabetes (<$Int2100 <$Int950 respectively).This comparative economic assessment has identified set population-wide individual inexpensive effective low settings.