Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): protocol for a cluster-randomised clinical trial of a complex intervention

• DOI: 10.1136/bmjopen-2017-020908
• Publication Date: 2019-09-20T15:48:26Z
• Authors: Alvin Richards-Belle; Paul R Mouncey; Dorothy Wade; Chris R Brewin; Lydia M Emerson; Richard Grieve; David A Harrison; Sheila Harvey; David Howell; Monty Mythen; Zia Sadique; Deborah Smyth; John Weinman; John Welch; Kathryn M Rowan
• Keywords: Critical Care; Cost-Benefit Analysis; Critical Illness; 150; 610; BF; Nurse's Role; RT; Stress Disorders, Post-Traumatic; 03 medical and health sciences; 0302 clinical medicine; Journal Article; Humans; Patient Reported Outcome Measures; Psychiatric Status Rating Scales; psychological intervention; PTSD; United Kingdom; 3. Good health; Psychotherapy; Critical care; Research Design; Intensive care; ICU; Linear Models; Quality of Life; mental health; RC

Introduction Acute psychological stress, as well unusual experiences including hallucinations and delusions, are common in critical care unit patients have been linked to post-critical morbidity such post-traumatic stress disorder (PTSD), depression anxiety. Little high-quality research has conducted evaluate interventions that could alleviate longer-term the setting. Our team developed piloted a nurse-led intervention, aimed at reducing patient-reported PTSD symptom severity other adverse outcomes 6 months, for evaluation POPPI trial. Methods analysis This is multicentre, parallel group, cluster-randomised clinical trial with staggered roll-out of intervention. The being carried out 24 (12 12 control) NHS adult, general, units UK evaluating effectiveness cost-effectiveness preventative intervention months. All sites deliver usual 5 months (baseline period). Intervention group then trained carry transition delivering rest recruitment period. Control duration also includes process independently team. Ethics dissemination protocol was reviewed approved by National Research Service South Central - Oxford B Committee (reference: 15/SC/0287). first patient recruited September 2015 results will be disseminated 2018. presented national international conferences published peer medical journals. Trial registration number ISRCTN53448131 ; Pre-results.