284 Obesity and type I endometrial carcinoma: an overly simplified model?

• DOI: 10.1136/ijgc-2020-igcs.244
• Publication Date: 2020-11-13T22:45:36Z
• Authors: C Liao; M Richardson; K Tran; C Chan; AK Mann; GL Maxwell; CA Hamilton; C Tian; K Darcy; DS Kapp; JK Chan
• Keywords: 2. Zero hunger; 3. Good health

<h3>Objective</h3> To evaluate the relationship between obesity and incidence of type I endometrial cancer in two large population cohorts. <h3>Methods</h3> From 2001 to 2016, rates were estimated from United States Cancer Statistics data. Hysterectomy, pregnancy, derived Behavioral Risk Factor Surveillance System (BRFSS). SEER*Stat Joinpoint regression used calculate rate (per 100,000). <h3>Results</h3> A total 531,481 patients diagnosed with cancer, 385,821 grade 1 or 2 endometrioid histology (82% White, 6% Black, 8% Hispanic, 3% Asian). Women aged 65–69 had highest (80.31). Incidence was White women (20.0), followed by Hispanics (15.1), Blacks (12.8), Asians (9.9). The overall carcinoma decreased 2% per year 24.4 18.5 2016 (p&lt;0.001). Using survey data BRFSS, proportion increased 21.1% 30.2% (average annual increase 2.3%, p&lt;0.001). Black (47.5%), (33.7%), Whites (28.1%), (12.8%). However, there no either over study period, association rate. <h3>Conclusion</h3> Older are at higher risk cancer. Our combined analyses suggest that decreasing is not correlated rise obesity.