514 Value of FDG-PET/CT for staging of locally advanced cervical cancer

• DOI: 10.1136/ijgc-2024-esgo.13
• Publication Date: 2024-03-10T18:12:09Z
• Authors: Marc Barahona; Lola Martí; Pilar Perlaza-Jim...; Sergi Fernández-G...; Juan Carlos Torrejón; Mireia Castilla; August Vidal; Dina Najjari-Namal; Milica Stefanovic; Beatriz Pardo; Marta Gil-Martin; Jordi Ponce
• Keywords: Lymphadenectomy

<h3>Introduction/Background</h3> Treatment of locally advanced cervical cancer (LACC) is based on radical external beam radio-chemotherapy (EBRT/CHT) or exclusive chemotherapy (CT) in stage IVB. EBRT fields can be pelvic extended depending lymph node involvement. Paraaortic lymphadenectomy(PAL) the 'Gold Standard' to asses paraaortic Positron Emission Tomography ([18]FDG-PET/CT) plays a role diagnosing retroperitoneal involvement and distant metastases. We aimed evaluate contribution FDG-PET/CT for staging LACC. <h3>Methodology</h3> From January 2013 December 2018 all patients diagnosed with LACC (clinical FIGO 2009 &gt;IB2) were included observational prospective database. All underwent whole-body primary staging. PAL Surgical approaches were: laparoscopic (LRP) robotic transperitoneal (RT). False positive (FP), false negative (FN), predictive value (NPV) (PPV) analyzed compared PAL. <h3>Results</h3> 103 9 (8,7%) metastases ( IVB) by confirmed biopsy. Therefore, those 8.7% patients, indication EBRT/CHT was changed CHT. 17 didn't due surgical complexity poor overall health. 77 (74,7%) (32 LRP - 45 RT) without statistically differences age, BMI, complications, number nodes. RT faster than (106min vs 135min p=00,7). PPV 57,1%, FP 42,9%, NPV 87,1%, FN 12,9% PET/CT In case Pelvic PA nodes FDG-PET/CT, 5,9%. However, 19,4% when + (table 1). <h3>Conclusion</h3> This study suggests that an effective imaging technique assess good except paraaortic. diagnoses almost 10% unsuspected (FIGO leading change treatment. <h3>Disclosures</h3> The authors have nothing disclose.