Motor neurone disease in the Lothian Region of Scotland 1961-81.

• DOI: 10.1136/jech.40.4.344
• Publication Date: 2008-11-12T20:09:01Z
• Authors: S M Holloway; J D Mitchell
• Keywords: Motor neurone disease; Etiology

One hundred and sixty one patients with motor neurone disease (MND), from the Lothian Region of Scotland, were studied in an attempt to identify factors important aetiology. Onset was between 1961 1981 incidence highest 1968 1975. The probability developing MND greatest ages 65 69, a greater proportion female than males had onset bulbar muscles. Some 5% positive family history MND. There no evidence that infective agents aetiology disease. suggestion patient group contained number electrical workers, food, drink tobacco rubber workers would have been expected. However, larger series be needed confirm increased susceptibility individuals engaged these occupations.