Serum enzyme studies in muscle disease: Part I Variations in serum creatine kinase activity in normal individuals

• DOI: 10.1136/jnnp.27.1.1
• Publication Date: 2008-11-10T20:53:49Z
• Authors: J. M. S. Pearce; R. J. Pennington; J. N. Walton
• Keywords: Creatine kinase; Creatine

It has been recognized for many years that in patients with muscular dystrophy there are sub- stantial increases the activity of certain enzymes, e.g., aldolase and transaminases, serum.Extensive surveys by several workers have shown changes particularly striking cases Duchenne type (decreasing as disease progresses), smaller limb-girdle facio-scapulo-humeral types dystrophy, slight or absent neurogenic weakness wasting (Dreyfus Schapira, 1955;