Identifying large ischemic core volume ranges in acute stroke that can benefit from mechanical thrombectomy

• DOI: 10.1136/neurintsurg-2020-016934
• Publication Date: 2020-12-17T02:14:09Z
• Authors: Takeshi Yoshimoto; Manabu Inoue; Kanta Tanaka; Kodai Kanemaru; Junpei Koge; Masayuki Shiozawa; Naruhiko Kamogawa; Shunsuke Kimura; Tetsuya Chiba; Tetsu Satow; Jun C Takahashi; Kazunori Toyoda; Masatoshi Koga; Masafumi Ihara
• Keywords: Stroke; Acute stroke

Background We aimed to identify the large ischemic core (LIC) volume ranges in acute stroke patients that can benefit from mechanical thrombectomy (MT). Methods Consecutive within 24 hours of onset anterior circulation with vessel occlusion and volumes 70–300 mL were included our single-center prospective database March 2014 December 2019. Subjects divided into three groups by baseline (A: 70–100 mL; B: 101–130 C: >130 mL). compared modified Rankin Scale (mRS) score 0–2 at 3 months parenchymal hematoma between receiving MT standard medical treatment (SMT), determined clinically treatable for MT. Results Of 157 (86 women; median age, 81 years; volume, 123 mL), 49 underwent In Group A (n=52), (n=31) showed a higher proportion mRS (52% vs 5%, P<0.05) versus SMT, respectively. B (n=36) (n=14) also had (29% 9%, P=0.13) C (n=69), only four received The 95% confidence intervals probability (n=49) SMT (n=108) intersected 120–130 mL. Conclusions Ischemic 70 100 may upper limit is approximately 120 selected LIC