Mechanical thrombectomy for acute ischemic stroke in COVID-19 patients: multicenter experience in 111 cases

• DOI: 10.1136/neurintsurg-2022-018723
• Publication Date: 2022-03-15T17:30:47Z
• Authors: Hanna Styczen; Volker Maus; Lukas Goertz; Martin Köhrmann; Christoph Kleinsc...; Sebastian Fischer; Markus Möhlenbruch; Iris Mühlen; Bernd Kallmünzer; Franziska Dorn; Asadeh Lakghomi; Matthias Gawlitza; Daniel Kaiser; Joachim Klisch; Donald Lobsien; Stefan Rohde; Gisa Ellrichmann; Daniel Behme; Maximilian Thormann; Fabian Flottmann; Laurens Winkelmeier; Elke R Gizewski; Lukas Mayer-Suess; Tobias Boeckh-Beh...; Isabelle Riederer; Randolf Klingebiel; Björn Berger; Martin Schlunz-He...; Dominik Grieb; Ali Khanafer; Richard du Mesnil...; Christophe Arendt; Jens Altenbernd; Jan-Ulrich Schlump; Adrian Ringelstein; Vivian Jean Marce...; Christian Loehr; Agnes Maria Dahlke; Carolin Brockmann; Sebastian Reder; Ulrich Sure; Yan Li; Ruben Mühl-Bennin...; Thomas Rodt; Kai Kallenberg; Alexandru Durutya; Mohamed Elsharkawy; Paul Stracke; Mathias Gerhard S...; Alexander Bock; Omid Nikoubashman; Martin Wiesmann; Hans Henkes; Pascal J Mosimann; René Chapot; Michael Forsting; Cornelius Deuschl
• Keywords: Stroke; Groin

Background Data on the frequency and outcome of mechanical thrombectomy (MT) for large vessel occlusion (LVO) in patients with COVID-19 is limited. Addressing this subject, we report our multicenter experience. Methods A retrospective cohort study was performed consecutive acute stroke infection treated MT at 26 tertiary care centers between January 2020 November 2021. Baseline demographics, angiographic clinical evaluated by modified Rankin Scale (mRS) discharge 90 days were noted. Results We identified 111 out 11 365 (1%) or subsided who underwent due to LVO. Cardioembolic events most common etiology LVO (38.7%). Median baseline National Institutes Health Stroke score Alberta Program Early CT Score 16 (IQR 11.5–20) 9 7–10), respectively. Successful reperfusion (mTICI ≥2b) achieved 97/111 (87.4%) 46/111 (41.4%) reperfused completely. The procedure-related complication rate 12.6% (14/111). Functional independence 20/108 (18.5%) 14/66 (21.2%) follow-up. in-hospital mortality 30.6% (33/108). In subgroup analysis, severe requiring intubation had a twice as high mild moderate infection. Acute respiratory failure ventilation time interval from symptom onset groin puncture independent predictors an unfavorable logistic regression analysis. Conclusion Our showed poor mortality, especially undergoing