Comparison of the Pipeline embolisation device alone or combined with coiling for treatment of different sizes of intracranial aneurysms

• DOI: 10.1136/svn-2021-001258
• Publication Date: 2022-05-09T18:48:30Z
• Authors: Chao Wang; Bin Luo; Tianxiao Li; Aisha Maimaitili; Guohua Mao; Donglei Song; Yunyan Wang; Wenfeng Feng; Yang Wang; Huaizhang Shi; Jieqing Wan; Jianmin Liu; Sheng Guan; Yuanli Zhao; Hongqi Zhang
• Keywords: Saccular aneurysm; Endovascular coiling

Objectives The aim of this study was to compare complications and outcomes between intracranial aneurysms treated with the Pipeline embolisation device (PED) alone or PED combined coiling for different-sized aneurysms. Method Patients by were collected from in China postmarket multicentre registry study. We performed a propensity match analysis efficacy safety treatment, then organised into three groups based on their size: small (≤7 mm), medium (≤15 mm >7 mm) large/giant (>15 mm). Complications aneurysm occlusion rates size compared patients. Result A total 1171 patients 1322 included. All received clinical follow-up, while angiographic follow-up available 967 For aneurysms, there no difference rate two (79.1% vs 88.4%, respectively), significant increase ischaemic complication (8.3% 19.3%, respectively, p=0.0001). saccular significantly improved (medium aneurysms: 74.7% 88.8%, p<0.0001; 72.9% 86.9%, p=0.018), differences rate. non-saccular showed differences. Conclusion Use adjunctive coils can improve without increasing