The Bionode

• DOI: 10.1145/3301310
• Publication Date: 2019-02-19T20:54:15Z
• Authors: Daniel J. Pederson; Christopher J. Qu...; Muhammad A. Arafat; Jesse P. Somann; Jack D. Williams; Rebecca A. Bercich; Zhi Wang; Gabriel O. Albors; John G. R. Jefferys; Pedro P. Irazoqui
• Keywords: 0301 basic medicine; 03 medical and health sciences; Mechanical Engineering

Implantable closed-loop neuromodulation devices for use in long-term chronic studies in a lab or clinical trial are expensive to acquire and difficult to modify for specific use cases. This article documents the design and fabrication of a wireless implantable device using only commercially available off-the-shelf (COTS) components. This device, called the Bionode, can record and transmit up to four channels of biopotential data while simultaneously providing biphasic constant-current stimulation. The Bionode is a viable, low-cost, reusable, and easily modifiable research tool with clinical implications that has gained widespread use in various research projects at Purdue University.