Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings.

• DOI: 10.1148/radiology.191.1.8134596
• Publication Date: 2014-07-08T20:39:41Z
• Authors: H J Aronen; I E Gazit; D N Louis; B R Buchbinder; F S Pardo; R M Weisskoff; G R Harsh; G R Cosgrove; E F Halpern; F H Hochberg
• Keywords: Vascularity; Cerebral blood volume

PURPOSE: To assess the utility of magnetic resonance (MR) cerebral blood volume (CBV) maps in evaluation gliomas. MATERIALS AND METHODS: CBV from 19 patients with histologically proved gliomas were calculated dynamic MR image sets acquired echo-planar spin-echo imaging after intravenous injection gadolinium-based contrast material. RESULTS: The maximum varied 0.82 to 5.40 high-grade group (n = 13) and 1.01 1.21 low-grade 6). difference was statistically significant. Maximum associated mitotic activity vascularity, but not cellular atypia, endothelial proliferation, necrosis, or cellularity. CONCLUSION: provided diagnostic information available conventional six cases offers a functional parameter for assessing glioma grade regions focal activity.