Effect of carbohydrate ingestion on glycogen resynthesis in human liver and skeletal muscle, measured by 13C MRS

• DOI: 10.1152/ajpendo.2000.278.1.e65
• Publication Date: 2017-12-22T08:30:51Z
• Authors: Anna Casey; Rob Mann; Katie Banister; John Fox; Peter G. Morris; Ian A. Macdonald; Paul L. Greenhaff
• Keywords: Adult; Male; Carbon Isotopes; Sucrose; Magnetic Resonance Spectroscopy; 03 medical and health sciences; Blood; Glucose; 0302 clinical medicine; Liver; Reference Values; Dietary Carbohydrates; Physical Endurance; Humans; Muscle, Skeletal; Oxidation-Reduction; Glycogen

This study investigated the effect of carbohydrate (CHO) ingestion on postexercise glycogen resynthesis, measured simultaneously in liver and muscle ( n = 6) by 13 C magnetic resonance spectroscopy, subsequent exercise capacity 10). Subjects cycled at 70% maximal oxygen uptake for 83 ± 8 min six separate occasions. At end exercise, subjects ingested 1 g/kg body mass (BM) glucose, sucrose, or placebo (control). Resynthesis over a 4-h period after treatment was first three occasions, occasions four through six. No resynthesized during control trial. Liver resynthesis evident glucose (13 g) sucrose (25 5 ingestion, both which were different from P < 0.01). significant differences found among trials. A relationship between CHO load (g) change content 30, 90, 150, 210 recovery r 0.59–0.79, P< 0.05). Furthermore, modest existed r= 0.53, However, no difference mean time (control: 35 5, glucose: 40 sucrose: 46 6 min). Therefore, BM is sufficient to initiate contributes capacity, but not resynthesis.