Aerobic exercise training-induced changes in serum C1q/TNF-related protein levels are associated with reduced arterial stiffness in middle-aged and older adults

• DOI: 10.1152/ajpregu.00212.2017
• Publication Date: 2017-10-25T11:11:56Z
• Authors: Natsuki Hasegawa; Shumpei Fujie; Naoki Horii; Masataka Uchida; Toshiyuki Kurihara; Kiyoshi Sanada; Takafumi Hamaoka; Motoyuki Iemitsu
• Keywords: Aerobic Exercise; Endurance Training

Adiponectin regulates endothelial nitric oxide synthase in cells, and body fat loss by aerobic exercise training promotes adiponectin secretion. Recently, C1q/tumor necrosis factor-related proteins (CTRPs) have been identified as novel adipokines are paralogs of adiponectin, but the association between training-induced reduction arterial stiffness circulating CTRPs levels remains unclear. This study aimed to clarify whether middle-aged older adults is associated with change serum induced training. A total 52 participants were randomly divided into two groups: a group ( n = 26) sedentary control 26). Participants completed 8 wk (60-70% peak oxygen uptake for 45 min, 3 days/wk). The percent whole fat, abdominal visceral area, carotid-femoral pulse-wave velocity (cfPWV) was significantly greater than P < 0.05). Moreover, increase CTRP3, CTRP5 from baseline higher compared Additionally, cfPWV negatively correlated r -0.51, -0.48, -0.42, respectively, 0.05), increased plasma nitrite/nitrate level only 0.41, These results suggest that may be adults.