Influence of exercise and fiber type on antioxidant enzyme activity in rat skeletal muscle

• DOI: 10.1152/ajpregu.1994.266.2.r375
• Publication Date: 2017-12-24T20:45:46Z
• Authors: S. K. Powers; D. Criswell; J. Lawler; L. L. Ji; D. Martin; R. A. Herb; G. Dudley
• Keywords: Fiber type; Muscle fibre; Skeletal Muscle Fibers

These experiments examined the influence of exercise intensity and duration on antioxidant enzyme activity in locomotor muscles differing fiber type composition. Nine groups female Sprague-Dawley rats (age 120 days) exercised 4 days/wk a motor-driven treadmill for 10 wk. The impact three levels (low, moderate, high: approximately 55, 65, 75% maximal oxygen consumption, respectively) (30, 60, 90 min/day) was assessed. Sedentary animals served as controls. Oxidative capacity soleus white red gastrocnemius assessed by measurement citrate synthase (CS) activity, evaluated assay total superoxide dismutase, catalase, glutathione peroxidase (GPX) activities. In all muscles, CS increased function duration. Furthermore, gastrocnemius, magnitude training-induced increase directly related to intensity. contrast, peak relatively independent Catalase not (P > 0.05) any muscle with training. Training-induced changes dismutase GPX activities were specific; specifically, training significantly < up 60 min/day. Conversely, significant increases occurred only; but data demonstrate that enzymes are specific.