Effect of a lysine-enriched diet onl-lysine transport by the brush-border membrane of the chicken jejunum

• DOI: 10.1152/ajpregu.1998.274.1.r69
• Publication Date: 2017-12-25T01:24:04Z
• Authors: M. Torras-Llort; J. F. Soriano-García; R. Ferrer; M. Moretó
• Keywords: Brush border

The influx ofl-lysine into apical vesicles from the chicken jejunum occurs through two systems, one with low Michaelis constant ( K m ) and features of system b 0,+ other relatively high forl-lysine properties y + . In present study effect a lysine-enriched diet (Lys, containing 68 g l-lysine/kg dietary protein, control animals 48 g/kg) onl-lysine uptake both transport systems was investigated. Results show that 1) lysine enrichment had no on either body weight or efficiency food utilization. 2) Lys-fed animals, mediatedl-lysine best fitted to two-system model activity. 3) presence an Na gradient, totall-lysine is significantly higher in than birds (about 40% increase). 4) Lys increases 6-fold (KSCN gradient) 12-fold (NaSCN maximum velocity V max by 6- 20-fold, respectively. effects -like are only observed gradient (30% 5) involved activation process chickens, but there correlation between external concentration l-lysine influx. conclusion, - upregulated different kinetic profiles; high-capacity carrier shows increase without changes , whereas low-capacity as well