Data from Factors Associated with False Positive Results on Screening Mammography in a Population of Predominantly Hispanic Women

• DOI: 10.1158/1055-9965.c.6516277.v1
• Publication Date: 2023-04-01T07:14:04Z
• Authors: Julia E. McGuinness; William Ueng; Meghna S. Trivedi; Hae Seung Yi; Raven David; Alejandro Vanegas; Jennifer Vargas; Rossy Sandoval; Rita Kukafka; Katherine D. Crew
• Keywords: Breast Cancer Screening

<div>Abstract<p><b>Background:</b> Potential harms of screening mammography include false positive results, such as recall breast imaging or biopsies.</p><p><b>Methods:</b> We recruited women undergoing at Columbia University Medical Center in New York, York. They completed a questionnaire on cancer risk factors and permitted access to their medical records. Breast status was determined using the Gail model family history screener. High defined 5-year invasive ≥1.67% eligible for <i>BRCA</i> genetic testing. False results were (BIRADS score 0, 3, 4, 5) and/or biopsies that did not yield cancer.</p><p><b>Results:</b> From November 2014 October 2015, 2,361 enrolled 2,019 evaluable, whom 76% Hispanic 10% non-Hispanic white. Fewer met high-risk criteria than whites (18.0% vs. 68.1%), but Hispanics more frequently engaged annual (71.9% 60.8%). Higher density (heterogeneously/extremely dense mostly fat/scattered fibroglandular densities) frequent (annual biennial) significantly associated with [odds ratio (OR), 1.64; 95% confidence interval (CI), 1.32–2.04 OR, 2.18; CI, 1.70–2.80, respectively].</p><p><b>Conclusions:</b> observed who screened had higher greater results. In addition, despite having lower compared whites.</p><p><b>Impact:</b> Our highlight need risk-stratified potentially minimize mammography. <i>Cancer Epidemiol Biomarkers Prev; 27(4); 446–53. ©2018 AACR</i>.</p></div>