Figure S1. from Plasma IL8 Is a Biomarker for TAK1 Activation and Predicts Resistance to Nanoliposomal Irinotecan in Patients with Gemcitabine-Refractory Pancreatic Cancer

• DOI: 10.1158/1078-0432.22477082.v1
• Publication Date: 2023-04-01T14:06:08Z
• Authors: Valeria Merz; Camilla Zecchetto; Raffaela Santoro; Francesca Simionato; Fabio Sabbadini; Domenico Mangiameli; Geny Piro; Alessandro Cavaliere; Michela Deiana; Maria Teresa Valenti; Diana Bazan; Vita Fedele; Sara Lonardi; Davide Melisi
• Keywords: CD68

<p>Immunohistochemical analysis. Serial paraffin sections from tumors excised mice orthotopically inoculated with AsPC1 pancreatic cancer cells transduced lentiviruses expressing shTAK1 (AsPC1shTAK1) or a scramble sequence as control (AsPC1ctrl) were stained antibodies to CD68 carboxylesterase-2 (CES2). We measured similarly minimal levels (less than 1 cell/field) of CD68+ morphological features tumor associated macrophages (TAM) and in specimens bearing AsPc1 if compared that tumors</p>