Data from TIL Therapy: Facts and Hopes

• DOI: 10.1158/1078-0432.c.6626950
• Publication Date: 2023-05-02T18:31:44Z
• Authors: Tine J. Monberg; Troels H. Borch; Inge M. Svane; Marco Donia
• Keywords: Tumor-infiltrating lymphocytes; Treatment modality

<div>Abstract<p>After a positive phase III trial, it is evident that treatment with tumor-infiltrating lymphocytes (TIL) safe, feasible, and effective modality for patients metastatic melanoma. Further, the safe feasible in diverse solid tumors, regardless of histologic type. Still, TIL has not obtained regulatory approvals to be implemented on larger scale. Therefore, its availability currently restricted few centers worldwide. In this review, we present current knowledge therapy discuss practical, logistic, economic challenges associated implementing Finally, suggest strategies facilitate widespread implementation approaches develop next generation TILs.</p></div>