Maternal Complications following Open Fetal Myelomeningocele Repair at the Zurich Center for Fetal Diagnosis and Therapy

• DOI: 10.1159/000494024
• Publication Date: 2018-11-14T22:01:25Z
• Authors: Franziska M. Winder; Ladina Vonzun; Martin Meuli; Ueli Moehrlen; Luca Mazzone; Franziska Krähenmann; Margret Hüsler; Roland Zimmermann; Nicole Ochsenbein...
• Keywords: Fetal Surgery; Chorioamnionitis

<b><i>Introduction:</i></b> Despite undoubtable benefits of open fetal myelomeningocele (fMMC) repair, there are considerable maternal risks. The aim this study was to evaluate and systematically categorize complications after fMMC repair. <b><i>Methods:</i></b> We analyzed data 40 repairs performed at the Zurich Center for Fetal Diagnosis Therapy. Maternal were classified according a 5-level grading system based on classification surgical proposed by Clavien Dindo. <b><i>Results:</i></b> observed no grade 5 complication (death patient). Five (12.5%) women demonstrated severe 4 complications: 1 case uterine rupture in nullipara 36 gestational weeks (GW), third-degree atrioventricular block which needed short mechanical resuscitation, bilateral lung embolism requiring intensive care unit (ICU) management due low-output syndrome, chorioamnionitis urosepsis both ICU 31 GW. Twenty-six (65%) had minor (grade 1–3) complications. <b><i>Conclusions:</i></b> Only one (uterine rupture, 2.5%) clear-cut direct consequence surgery. other four (10%) occurred context of, but cannot unequivocally be attributed to, surgery, since they may occur also circumstances. used is tenable step towards stringent documentation