Liver injury in COVID-19: pathological findings

• DOI: 10.11604/pamj.2022.41.56.31114
• Publication Date: 2022-01-20T11:42:04Z
• Authors: Mouna Zghal; Marwa Bouhamed; Manel Mellouli; Meriam Triki; Rim Kallel; Lobna Ayedi; Tahya Sellami Bou...; Saadia Makni
• Keywords: 0301 basic medicine; 03 medical and health sciences; Liver; SARS-CoV-2; Commentary; COVID-19; Humans; Liver; COVID-19; injury; pathology; 3. Good health

Hepatic injuries have been reported in patients with Coronavirus disease 2019 infection, particularly in those with moderate to severe illness. To date, pathological changes caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in liver tissue are unclear. Moreover, the mechanisms involved in liver injury in Coronavirus disease 2019 infection are not yet established. In this paper, we summarize the spectrum of pathologic findings of liver injury in patients infected by SARS-CoV-2 and we discuss the clinicopathological correlation and the mechanisms of liver damage in Coronavirus disease 2019 infection.