Oxidative stress is associated with markers of renal dysfunction in children aged 6-9 years old in a South African population.

• DOI: 10.11604/pamj.2022.42.35.26443
• Publication Date: 2022-01-01
• Authors: Edna N. Matjuda; Godwill Azeh Engwa; Muhau Muhulo Mung...; Constance R. Sewa...; Benedicta Ngwechi...
• Keywords: Albuminuria; Microalbuminuria; TBARS

although studies have shown a relationship between albuminuria and oxidative stress in adults, limited information on the subject is available children. The aim of this study was to assess South African children ancestry.a cross-sectional involving 6-9 years old randomly selected rural urban schools Eastern Cape Province Africa conducted. Anthropometric measurements were done urine samples collected for determination titres albumin, creatinine, 8-hydroxy-2-deoxy-guanosine (8-OHdG) thiobarbituric acid reactive substances (TBARS). urinary albumin creatinine ratio (ACR) calculated used determine albuminuria.creatinine 8-OHdG significantly higher (p<0.05) than while ACR TBARS compared prevalence 14.05% which microalbuminuria 8.83% macroalbuminuria 5.22%. Albuminuria their counterparts more prevalent females. positively associated with cohort as well females cohort.findings showed that markers renal dysfunction 14% observed ancestry.