Embolization of Intracranial Aneurysms With Hydrogel-Coated Coils Versus Inert Platinum Coils

• DOI: 10.1161/01.str.0000221314.55144.0b
• Publication Date: 2006-05-05T01:17:21Z
• Authors: Ron C. Gaba; Sameer A. Ansari; Soma Sinha Roy; Franklin A. Marden; Marlos A.G. Viana; Tim W. Malisch
• Keywords: Inert

Background and Purpose— The durability of aneurysm coil embolization is thought to depend on packing density. expansile property hydrogel coating coils increases volumetric per length. We describe our experience using hydrogel-coated (HydroCoils) compared with inert platinum in intracranial embolization. Methods— Fifty aneurysms embolized primarily HydroCoils from 2003 2004 were 57 volume- shape-matched treated standard 2000 2003. Outcome measures included percentage occlusion (VPO), length number used, procedure time, fluoroscopy contrast volume, cost, hospital stay, therapy. Results— Seventeen/26/5 small/medium/large matched 29/24/4 platinum. HydroCoil yielded significantly greater VPO (84.8% versus 29.8%; P <0.001), decreased average total used (33.2 44.3 cm), reduced time (53.2 65.2 minutes; =0.016), but increased volume (174.8 112.9 cc; <0.001). There no differences stay. Procedure-related morbidity mortality rates the cohort 4% 0%, respectively. Follow-up angiography at mean 12.3 months revealed lower recurrence (17% 24%; number-needed-to-treat [NNT] 14.3). Initial costs associated higher ($5835 $4017; =0.004) countered by retreatment (10% 17%; NNT Conclusions— achieves density data favor HydroCoils, rates.