Further comments on the measurement of carotid stenosis from angiograms. North American Symptomatic Carotid Endarterectomy Trial (NASCET) Group.

• DOI: 10.1161/01.str.25.12.2445
• Publication Date: 2011-06-17T20:08:03Z
• Authors: M Eliasziw; R F Smith; N Singh; D W Holdsworth; A J Fox; H J Barnett
• Keywords: Stroke; Endarterectomy

Three different methods for estimating the percentage of reduction in diameter internal carotid artery (ie, stenosis) have been proposed literature. Further comparisons were carried out with intent recommending a current standard determining stenosis from angiograms. Angiograms 112 patients obtained. For each angiogram, was estimated manner European Carotid Surgery Trial (ECST method), North American Symptomatic Endarterectomy (NASCET and by method using common lumen (CC method). Although there is much discrepancy among estimates arising three any particular patient, it possible to predict (on average) one another. The relationship between NASCET CC linear, mean ratio distal 0.62 (SD 0.11). variability stabilizes only beyond 2.5 units (approximately 20 30 mm conventional angiography) proximal bifurcation. Unexpectedly, relationships both ECST parabolic (P < .001). reasons underlying these departures linearity are uncertain. comparability our results those reported literature regarding provides further evidence reproducibility measuring anatomic features that can be visualized on an angiogram. Disease important causes ischemic symptoms. Measuring narrowest portion relative normal same artery, well bulb, logical method. Moreover, benefits endarterectomy 70% 99% as determined established clinical trial. Converting method, given neither superior nor easier calculate, not recommended.