Abstract 14896: Does Echocardiography/Doppler Reliably Predict Elevated LVEDP?

• DOI: 10.1161/circ.132.suppl_3.14896
• Publication Date: 2024-04-23T10:56:22Z
• Authors: David M Cameron; David Bach; Vallerie McLaughlin; Melvyn Rubenfire; Scott Visovatti
• Keywords: Preload

Introduction: Heart failure with preserved ejection fraction is a common cause of group 2 pulmonary hypertension (PH). The utility echocardiography (echo)/ Doppler for identification elevated left ventricular end-diastolic pressure (LVEDP) specifically among patients PH not well defined. Methods: 161 referred to Pulmonary Hypertension Clinic were retrospectively studied. Included underwent echo/Doppler and had catheter measurement LVEDP or capillary wedge within 3-month period, normal sinus rhythm at the time TTE, unchanged diuretic regimens during examination interval. ability echo predict (> 15 mm Hg) based on American Society Echocardiography (ASE) / European Association (EAE) guidelines was evaluated, new model developed better prediction data using univariate linear regression multi-variable logistic regression; receiver operating characteristics analyzed. Results: Of patients, 81 (51%) > Hg invasive testing; mean PAP 37.8 ± 14.3 mmHg PVR 4.6 ±3.8 WU. E/A, E/e’ (septal, lateral, average), e’/a’ (lateral LA volume, diameter significant correlation (p values < 0.05). There poor test performance both ASE/EAE experimental (area under ROC 0.7, p 0.001). Only grade III significantly different from other grades value Conclusions: Numerous measurements correlate LV filling pressure. However, our that did permit confident LVEDP. Assessment adequate either reliably include exclude as severe PH.