Abstract 066: A Healthy Plant-based Diet Was Associated With Slower Cognitive Decline In African Americans: A Biracial Community-based Cohort Of Older Adults

• DOI: 10.1161/circ.145.suppl_1.066
• Publication Date: 2022-04-07T15:49:21Z
• Authors: Xiaoran Liu; Klodian Dhana; Lisa Barnes; Christy Tangney; Puja Aggarwal; Neelum Agarwal; Thomas Holland; Kumar Rajan
• Keywords: Cognitive Decline

Background: African Americans (AAs) are about twice as likely to develop dementia compared non-Hispanic whites (NHWs). Dietary modification is an effective preventive strategy reduce the rate of cognitive decline, a hallmark feature dementia; however, evidence from diverse populations focusing on AAs minimal. Objective: To evaluate association between plant-based diet and decline in population-based sample NHWs. Method: This study consisted 4753 participants (62% American, 63% female) biracial United States (Chicago Health Aging Project, 1993 2012). Plant-based quality was evaluated by overall index (PDI), healthful PDI (hPDI), unhealthful (uPDI). Global cognition assessed using composite score four tests cognition. We used mixed models examine PDI, hPDI, uPDI with global cognition, perceptual speed, episodic memory. Models were adjusted for age, sex, apoE genotype, education, activities, smoking status, calorie intake, risk factors cardiovascular disease, time, interaction term time each covariate. Results: demonstrated that there distinct differences dietary patterns had higher intakes egg, fish or seafood, sugar-sweetened beverages, whole grains NHWs (p<0.001 all). Higher hPDI associated slower memory but not highest quintile significantly rates β = 0.0183 (p=0.032), speed 0.0179 (p=0.04), β=0.0183 (p=0.04) individuals lowest hPDI. The slowed 28.4% when AAs. There no associations either racial group. Conclusion: have patterns. A healthy These results informative facilitating development tailored recommendations prevention populations.