Abstract 18559: Sex Differences In Acute Myocardial Infarction Related Cardiogenic Shock Across Different Levels Of Care

• DOI: 10.1161/circ.148.suppl_1.18559
• Publication Date: 2023-12-19T08:12:47Z
• Authors: Sajal Datta; Apurva Sharma; Kylie Roslin; Rebecca Smoller; sana ahmad; Moein Mokhtari; Gerin R Stevens; Simon Maybaum; Miguel Alvarez Vi...
• Keywords: Impella

Background Previous registry data have suggested important sex-based differences in management and clinical outcomes for patients with acute myocardial infarction related cardiogenic shock (AMI-CS). Methods: We classified 11 hospitals a metropolitan health network as different levels of care (LOC) CS based on their highest mechanical circulatory support (MCS) capability; L1: Durable LVAD, L1A: ECMO, L2: Impella. identified all ≥ 18 years age treated AMI-CS (ICD-10 diagnosis codes) from 2016 to 2022. Sex hospital are reported. Descriptive statistics logistic regression were performed using PRISM version 9. Results: In our cohort (n=1,956), women minority L1 (30%) L1A (31%) L2 (41%) older decreasing LOC, 72y. (61-81), 74y. (64-82) 81y. (72-88), p<0.01 trend.Across left heart catheterization (LHC) percutaneous coronary interventions (PCI) used similarly men, while artery bypass grafting (CABG) surgical centers (L1 L1A) MCS PCI (except more frequently men (Figure). After adjustment LOC other relevant covariates, female sex (aOR: 1.35, 95%CI: 1.09-1.67; p=0.007), 1.04, 1.03-1.05, p<0.001) admission cardiac arrest 5.36, 3.63-8.54, associated higher mortality. Conclusion: system, despite similar rates LHC across received less CABG than had adjusted