Electrocardiograms in Healthy North American Children in the Digital Age

• DOI: 10.1161/circep.117.005808
• Publication Date: 2018-06-21T09:05:36Z
• Authors: Elizabeth V. Saarel; Suzanne Granger; Jonathan R. Kaltman; L. LuAnn Minich; Martin Tristani-F...; Jeffrey J. Kim; Kathleen Ash; Sabrina S. Tsao; Charles I. Berul; Elizabeth A. Step...; David G. Gamboa; Felicia Trachtenberg; Peter Fischbach; Victoria L. Vetter; Richard J. Czosek; Tiffanie R. Johnson; Jack C. Salerno; Nicole B. Cain; Robert H. Pass; Ilana Zeltser; Eric S. Silver; Joshua R. Kovach; Mark E. Alexander
• Keywords: Age groups; Black male; Black female; Reference values

Interpretation of pediatric ECGs is limited by lack accurate sex- and race-specific normal reference values obtained with modern technology for all ages. We sought to obtain contemporary digital ECG measurements in healthy children from North America, evaluate the effects sex race, compare our results commonly used published datasets.Digital (12-lead) were retrospectively collected ≤18 years old echocardiograms at 19 centers Pediatric Heart Network. Patients classified into 36 groups: 6 age, 2 sex, 3 race (white, black, other/mixed) categories. Standard intervals amplitudes measured; mean±SD 2nd/98th percentiles determined age group, race. For each parameter, multivariable analysis, stratified was conducted using as predictors. Parameters compared large data sets.Among 2400 children, significant differences found The corrected QT interval lead II greater girls boys groups ≥3 (P≤0.03) whites blacks ≥12 (P<0.05). R wave amplitude V6 (P<0.001), white or other categories (P≤0.006), a public set (P<0.0001).In this large, diverse cohort most varied These have important implications interpreting era when diagnosis screening, including thresholds left ventricular hypertrophy.