Pulsed Field Ablation of Paroxysmal Supraventricular Tachycardia: A Prospective Multicenter Single-Arm Study in China

• DOI: 10.1161/circep.124.013206
• Publication Date: 2024-11-29T10:01:44Z
• Authors: Fanghui Li; Aobo Gong; Hongde Hu; Kaijun Cui; Qing Yang; Xiaobo Pu; Shi Chen; Jian Jiang; Hua Fu; Hanxiong Liu; Yuehui Yin; Qiangsun Zheng; Maoqin Shu; Chun Gui; Jian Xu; Pingzhen Yang; Zhiyu Ling; Hongzhi Wang; Tingting Yang; Rongzheng Yue; Jinnian Gao; Xiaolin Zhu; Tiancai Shi; Wentao Li; Xianjin Hu; Yao Tong; Qing Zhang; Rui Zeng
• Keywords: Atrioventricular reentrant tachycardia; Supraventricular Tachycardia; Atrioventricular node; Atrioventricular block

BACKGROUND: Pulsed field ablation (PFA) has gained attention in cardiac electrophysiology, but data on its application to paroxysmal supraventricular tachycardia are limited. This study aimed assess the feasibility and safety of PFA combination with radiofrequency for treating tachycardia. METHODS: A prospective, multicenter, single-arm was conducted across 8 centers China. Patients atrioventricular nodal reentrant tachycardia, or Wolff-Parkinson-White syndrome underwent using a focal point dual-mode PFA/radiofrequency catheter. used achieve acute success, consolidation near-His accessory pathways far-His pathways. Primary secondary end points were success 180-day follow-up respectively. RESULTS: total 158 patients (77 63 16 Wolff-Parkinson-White, 2 both tachycardia) completed trial. Acute successful 157 (99.37%). The skin-to-skin procedure time 89.9±35.5 min. median number discharges 12 (8–19) effective discharge 4.6 (3.2–6.4) ms. Five (4 1 syndrome) experienced recurrence during period. One patient had transient first-degree block resolving hours, one third-degree 24 hours. No permanent other adverse events occurred CONCLUSIONS: demonstrated treatment SVT. Reversible first- blocks observed following each. preliminary results indicated although it is impossible determine relative contribution PFA.