EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography–Based Management in Plaque Erosion)

• DOI: 10.1161/circinterventions.117.005860
• Publication Date: 2017-12-16T01:10:53Z
• Authors: Lei Xing; Erika Yamamoto; Tomoyo Sugiyama; Haibo Jia; Lijia Ma; Sining Hu; Chao Wang; Yingchun Zhu; Lulu Li; Maoen Xu; Huimin Liu; Krzysztof Bryniarski; Jingbo Hou; Shaosong Zhang; Hang Lee; Bo Yu; Ik-Kyung Jang
• Keywords: Fibrous cap

The initial EROSION study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion) demonstrated that patients with acute coronary syndrome caused by plaque erosion might be stabilized aspirin and ticagrelor without stenting for ≤1 month. However, a long-term evaluation of outcomes is lacking. aim this was to assess whether the benefit noninterventional therapy maintained year.Among 53 who completed clinical follow-up, 49 underwent repeat optical coherence tomography imaging at 1 year. Median residual thrombus volume decreased significantly from month year (0.3 mm3 (0.0-2.0 mm3] versus 0.1 [0.0-2.0 mm3]; P=0.001). Almost half (46.9%) had no Minimal effective flow area remained unchanged (2.1 mm2 [1.5-3.8 mm2] 2.1 [1.6-4.0 mm2]; P=0.152). Among patients, (92.5%) free major adverse cardiovascular event year: 3 (5.7%) required revascularization because exertional angina (1.9%) patient gastrointestinal bleeding.One-year follow-up further decrease between 1-month 1-year follow-up. A majority managed year.URL: https://www.clinicaltrials.gov. Unique identifier: NCT02041650.