Management of Myocardial Revascularization in Patients With Stable Coronary Artery Disease Undergoing Transcatheter Aortic Valve Implantation

• DOI: 10.1161/circinterventions.122.012417
• Publication Date: 2022-12-20T19:00:40Z
• Authors: Giuliano Costa; Thomas Pilgrim; Ignacio J. Amat S...; Ole De Backer; Won-Keun Kim; Henrique Barbosa ...; Francesco Saia; Matjaz Bunc; Didier Tchetche; Philippe Garot; Flavio Luciano Ri...; Dzxcfewarren Mylotte; Francesco Burzotta; Yusuke Watanabe; Federico De Marco; Tullio Tesorio; Tobias Rheude; Marco Tocci; Anna Franzone; Roberto Valvo; Mikko Savontaus; Hendrik Wienemann; Italo Porto; Caterina Gandolfo; Alessandro Iadanza; Alessandro Santo ...; Markus Mach; Azeem Latib; Luigi Biasco; Maurizio Taramasso; Marco Zimarino; Daijiro Tomii; Philippe Nuyens; Lars Sondergaard; Sergio F. Camara; Tullio Palmerini; Mateusz Orzalkiewicz; Klemen Steblovnik; Bastien Degrelle; Alexandre Gautier; Paolo Alberto Del...; Andrea Mainardi; Michele Pighi; Mattia Lunardi; Hideyuki Kawashima; Enrico Criscione; Vincenzo Cesario; Fausto Biancari; Federico Zanin; Michael Joner; Giovanni Esposito; Matti Adam; Eberhard Grube; Stephan Baldus; Vincenzo De Marzo; Elisa Piredda; Stefano Cannata; Fortunato Iacovelli; Martin Andreas; Valentina Frittitta; Elena Dipietro; Claudia Reddavid; Orazio Strazzieri; Silvia Motta; Domenico Angellotti; Carmelo Sgroi; Faraj Kargoli; Corrado Tamburino; Marco Barbanti
• Keywords: Unstable angina; Stroke

The best management of stable coronary artery disease (CAD) in patients undergoing transcatheter aortic valve implantation (TAVI) is still unclear due to the marked inconsistency available evidence.The REVASC-TAVI registry (Management Myocardial Revascularization Patients Undergoing Transcatheter Aortic Valve Implantation With Coronary Artery Disease) collected data from 30 centers worldwide on TAVI who had significant, CAD at preprocedural work-up. For purposes this analysis, with either complete or incomplete myocardial revascularization were compared a propensity score matched take into account baseline confounders. primary and co-primary outcomes all-cause death composite death, stroke, infarction, rehospitalization for heart failure, respectively, 2 years.Among 2407 enrolled, 675 pairs achieving matched. (21.6% versus 18.2%, hazard ratio' 0.88 [95% CI, 0.66-1.18]; P=0.38) (29.0% 27.1%, 0.97 0.76-1.24]; P=0.83) outcome did not differ between revascularization, respectively. These results consistent across different prespecified subgroups (< >75 years age, Society Thoracic Surgeons > <4%, angina baseline, diabetes, left ventricular ejection fraction <40%, New York Heart Association class I/II III/IV, renal proximal CAD, multivessel main/proximal anterior descending CAD; all P values interaction >0.10).The present analysis showed that, among significant found during work-up, completeness achieved staged concomitantly was similar strategy reducing risk cause as well failure years, regardless clinical anatomical situations.