Risk Factors for Acute Myocardial Infarction in Latin America

• DOI: 10.1161/circulationaha.106.633552
• Publication Date: 2007-03-05T21:58:01Z
• Authors: Fernando Lanas; Alvaro Avezum; Leonelo E. Bautista; Rafael Diaz; Max Luna; Shofiqul Islam; Salim Yusuf
• Keywords: Abdominal obesity

Current knowledge of the impact cardiovascular risk factors in Latin America is limited.As part INTERHEART study, 1237 cases first acute myocardial infarction and 1888 age-, sex-, center-matched controls were enrolled from Argentina, Brazil, Colombia, Chile, Guatemala, Mexico. History smoking, hypertension, diabetes mellitus, diet, physical activity, alcohol consumption, psychosocial factors, anthropometry, blood pressure recorded. Nonfasting samples analyzed for apolipoproteins A-1 B-100. Logistic regression was used to estimate multivariate adjusted odds ratios (ORs) their 95% confidence intervals (CIs). Persistent stress (OR, 2.81; CI, 2.07 3.82), history hypertension 2.39 3.31), mellitus 2.59; 2.09 3.22), current smoking 2.31; 1.97 2.71), increased waist-to-hip ratio (OR versus third tertile, 2.49; 3.14), apolipoprotein B 1.83 2.94) associated with higher infarction. Daily consumption fruits or vegetables 0.63; 0.51 0.78) regular exercise 0.67; 0.55 0.82) reduced Abdominal obesity, abnormal lipids, high population-attributable risks 48.5%, 40.8%, 38.4%, respectively. Collectively, these accounted 88% risk.Interventions aimed at decreasing behavioral lowering pressure, modifying lipids could have a large on among Americans.