Association of Incident Cardiovascular Disease With Periodic Limb Movements During Sleep in Older Men

• DOI: 10.1161/circulationaha.111.038968
• Publication Date: 2011-08-23T04:53:46Z
• Authors: Brian B. Koo; Terri Blackwell; Sonia Ancoli-Israel; Katie L. Stone; Marcia L. Stefanick; Susan Redline
• Keywords: Aged, 80 and over; Male; Sleep Wake Disorders; Incidence; Polysomnography; Nocturnal Myoclonus Syndrome; 3. Good health; Cohort Studies; 03 medical and health sciences; Treatment Outcome; 0302 clinical medicine; Cardiovascular Diseases; Humans; Sleep; Aged; Follow-Up Studies

Periodic limb movements during sleep (PLMS) cause repetitive sympathetic activation and may be associated with increased cardiovascular risk. We hypothesized that PLMS frequency (periodic movement index [PLMI]) arousal [PLMAI]) are predictive of incident disease, including coronary heart peripheral arterial cerebrovascular in an elderly male cohort.