Early Left Ventricular Unloading or Conventional Approach After Venoarterial Extracorporeal Membrane Oxygenation: The EARLY-UNLOAD Randomized Clinical Trial

• DOI: 10.1161/circulationaha.123.066179
• Publication Date: 2023-10-18T09:00:33Z
• Authors: Min Chul Kim; Yongwhan Lim; Seung Hun Lee; Yoonmin Shin; Joon Ho Ahn; Dae Young Hyun; Kyung Hoon Cho; Doo Sun Sim; Young Joon Hong; Ju Han Kim; Myung Ho Jeong; Yong Hun Jung; In-Seok Jeong; Youngkeun Ahn
• Keywords: Interquartile range; Impella; Afterload

Although venoarterial extracorporeal membrane oxygenation (VA-ECMO) is beneficial for the treatment of profound cardiogenic shock, peripheral VA-ECMO cannulation can increase left ventricular afterload, thus compromising myocardial recovery. We investigated whether early routine unloading reduce 30-day mortality compared with conventional approach in patients shock undergoing VA-ECMO.