Omics and Extreme Phenotyping Reveal Longitudinal Association Between Left Atrial Size and Pulmonary Vascular Resistance in Group 2 Pulmonary Hypertension

• DOI: 10.1161/jaha.123.031746
• Publication Date: 2023-11-28T11:28:32Z
• Authors: Neil J. Kelly; David Newhouse; Himal Chapagain; Ashish Patel; Yicheng Tang; Ato Howard; Anna Kirillova; Hee‐Jung J. Kim; Haris Rahman; Wadih El Khoury; Seyed Mehdi Nouraie; Gavin Hickey; Leyla Elif Sade; Sandeep Jain; Stephen Y. Chan
• Keywords: Cardiac catheterization; Body surface area

Left heart disease is the most common cause of pulmonary hypertension (PH) and frequently accompanied by increases in vascular resistance. However, distinction between phenotypes PH due to left with a normal or elevated resistance-isolated postcapillary (IpcPH) combined pre- (CpcPH), respectively-has been incompletely defined using unbiased methods.